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The results of LYSTO have been published on the IEEE JBHI journal. If you are using the LYSTO dataset, you can cite it as follows:

*Y. Jiao et al., "LYSTO: The Lymphocyte Assessment Hackathon and Benchmark Dataset," in IEEE Journal of Biomedical and Health Informatics, vol. 28, no. 3, pp. 1161-1172, March 2024, doi: 10.1109/JBHI.2023.3327489. *

The LYSTO hackathon was held in conjunction with the Second MICCAI COMPAY Workshop on Computational Pathology on October 13, 2019 in Shenzhen, China.

This website and the LYSTO challenge will be kept open as an Educational Challenge on this website, as well as the evaluation procedure.

All methods developed during the hackathon will be summarized in a journal publication that will be submitted to a high-impact journal. 

For other questions, you can contact Dr. Francesco Ciompi.

Lymphocyte Assessment Hackathon

The LYmphocyte aSsessmenT hackathOn (LYSTO) is a challenge on the assessment of lymphocytes  in immunohistochemically stained tissue sections that was organized in conjunction with the COMPAY 2019 workshop.

The task of this challenge is automatic assessment of lymphocytes in tissue sections of several types of cancer  in human specimens stained with CD3 and CD8 immunohistochemistry. This is an important component of prognostic markers that are likely to be adopted in routine diagnostics in the near future. As an example, in the field of colorectal carcinoma, a prognostic marker based on such quantification already exists and is known as Immunoscore.

Hackathon timeline:

  • Small (pilot) dataset released: August 6, 2019
  • Automatic evaluation of pilot test set released: September, 2019.
  • Full training dataset released: October 4, 2019
  • Closed for new registrations: October 6, 2019
  • Teams of participants formed/method development in teams: October 6 - October 13, 2019
  • Full test set (on site) release/hackathon (in parallel with the COMPAY workshop): October 13, 2019


This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

The LYSTO hackathon is supported by: